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In conclusion, although there is substantial evidence in animals that numerous selenoproteins (e.g., mGPX4, nGPX4, GPX5, TXNRD3, selenoprotein P) are crucial for normal male reproductive function, and that their deficit (genetic knockdown) leads to reduced or total infertility, the studies in humans are still scarce

The Bencao Gangmu (1596 CE) mentioned that Chuanxiong and Danggui were used in ancient times to treat headaches (19)

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For humans dealing with chronic stress, this cortisol-lowering effect could have significant implications for sleep quality, body composition, and overall health

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